Background

The GRACE initiative has been launched to develop good practice principles for observational studies of comparative effectiveness through collaboration of knowledgeable people from academia, government, and the private sector. The goal of these principles is to enhance quality and facilitate the use of observational research to support decision-making by patients, physicians, and payers.

A key part of the GRACE initiative is creating a web-based, freely accessible library of real-world case studies that illustrate how observational comparative effectiveness studies can be used to support decision-making for product access, formulary placement, treatment guidelines or any other significant decisions relating to approval for payments or adopting use.

The library of case studies can be accessed using the links at the left. Case studies are organized into two categories: Drug, and Device. New case studies will be added on an ongoing basis.